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Vascular

Pulmonary Embolism

A blockage in one of the pulmonary arteries in your lungs, usually caused by blood clots that travel from the legs.

Pulmonary embolism (PE) occurs when a blood clot — most often from the deep leg veins — travels to the lungs and blocks blood flow. It is a medical emergency requiring urgent diagnosis and treatment.

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Diagram illustrating a blood clot blocking a pulmonary artery in the lungs

A pulmonary embolism is a life-threatening medical emergency where a blood clot obstructs blood flow in the lungs, requiring immediate treatment.

Symptoms

  • Sudden breathlessness
  • Chest pain, especially on deep breathing
  • Rapid heart rate
  • Coughing up blood
  • Light-headedness or collapse in severe cases

Risk Factors

  • Deep vein thrombosis
  • Prolonged immobility or recent surgery
  • Active cancer
  • Pregnancy
  • Inherited clotting disorders

Diagnosis

  • CT pulmonary angiography (CTPA) — gold standard
  • D-dimer blood test
  • ECG and echocardiography
  • V/Q lung scan for patients with contrast allergy or kidney impairment

Treatment Options

  • Anticoagulation with DOACs (rivaroxaban or apixaban) as first-line
  • Systemic thrombolysis for high-risk massive PE
  • Catheter-directed thrombolysis or mechanical thrombectomy
  • Long-term anticoagulation to prevent recurrence

Concerned About Pulmonary Embolism?

Dr. Peter Chang offers specialist assessment and personalised management at Paragon Medical Centre, Singapore.